ICMR - NIRBI


ICMR - National Institute for Research
in Bacterial Infections

आईसीएमआर - राष्ट्रीय जीवाणु संक्रमण अनुसंधान संस्थान

Department of Health Research, Ministry of Health and Family Welfare, Government of India
स्वास्थ्य अनुसंधान विभाग, स्वास्थ्य और परिवार कल्याण मंत्रालय, भारत सरकार
WHO Collaborating Centre For Research and Training On Diarrhoeal Diseases

BETI BACHAO BETI PADHAO
G20

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NICED : Scientists

  1. NICED
  2. Scientists
Dr. Saibal Das

Dr Saibal Das


 

General Information
Name Dr Saibal Das
Designation Scientist D
Division  
Specialization  
Date of joining ICMR  
Date of joining the present post  
Phone: +91 80724 86512
Email : saibal.das@icmr.gov.in, saibaldas123@gmail.com
Institute: : Indian Council of Medical Research National Institute for Research in Bacterial Infections (ICMRNIRBI)
MBBS: Nil Ratan Sircar Medical College & Hospital, Kolkata (20052011)
MD (Pharmacology): CMC, Vellore (20142017)
DM (Clinical Pharmacology): JIPMER, Puducherry (20172020)

Profile

Research Experience

Sr. No. Role / Position Institution / Organization Duration Research Focus / Key Contributions
1 Scientist D (Medical) ICMRNIRBI, Kolkata Apr 2025 Present Leading clinical research projects, evidence synthesis, training, and administrative responsibilities
2 Scientist D (Medical) ICMRCentre for Ageing and Mental Health, Kolkata Apr 2022 Apr 2025 Conducted research on ageing, pharmacoepidemiology, clinical pharmacology, and medication safety
3 Scientist D (Medical) ICMR Headquarters, New Delhi Jul 2021 Apr 2022 Central coordination of national-level research projects, clinical trials, and drug development
4 Regional Medical Advisor GSK Pharmaceuticals Ltd., Mumbai Aug 2020 Jul 2021 Managed medical & regulatory affairs, supervised Phase IV trials, pharmacovigilance, and bioequivalence studies
5 Senior Resident (Academic) Dept. of Clinical Pharmacology, JIPMER, Puducherry Jul 2017 Jul 2020 Conducted clinical trials, patient care services, therapeutic drug monitoring, and teaching
6 Post Graduate Registrar Dept. of Pharmacology &Clinical Pharmacology, CMC, Vellore Apr 2014 Mar 2017 Engaged in pre-clinical & clinical research, drug safety, and pharmacogenomics
7 Research Student Calcutta School of Tropical Medicine, Kolkata Mar Oct 2011 Pre-clinical research in pharmacology and tropical medicine
8 Medical Officer (NRHM) Nalmuri Block Primary Health Centre, WB Dec 2012 Mar 2014 Conducted field-level clinical research while providing primary care
9 Resident Medical Officer Repose Clinic & Research Centre Pvt. Ltd., Kolkata 20112012 Patient care services with research contributions in clinical pharmacology
 
10 Junior Resident NRS Medical College & Hospital, Kolkata Jul 2011 Mar 2012 Emergency care, exposure to clinical pharmacology applications in real-world settings

Research Interests

My research primarily focuses on the rational and evidence-based use of medicines across diverse populations. I am deeply engaged in designing and conducting clinical trials, observational studies, and systematic reviews to generate high-quality real-world evidence on the efficacy, effectiveness, and safety of drugs. My interests extend to pharmacogenomics and precision medicine, aiming to optimize individualized therapy. I actively contribute to antibiotic stewardship, pharmacovigilance, and drug development initiatives. By integrating clinical pharmacology with public health, I aim to generate real-world evidence that informs guidelines and improves antimicrobial use for better patient outcomes. Additionally, I explore health systems and policy-related aspects of medicine use, with a strong commitment to improving patient safety, ensuring equitable access, and advancing translational research for public health impact.

Memberships

National Societies

  1. Indian Public Health Association (IPHA)
  2. Epidemiology Foundation of India (EFI)
  3. Forum for Ethics Review Committees in India (FERCI)
     

International Societies

  1. WHO Global Patient Safety Network
  2. International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT)
  3. International Society for Pharmacoeconomics and Outcomes Research (ISPOR)
  4. International Society for Pharmacoepidemiology (ISPE)
  5. International Headache Society (IHS)
     

Awards

National Awards

  1. Two Global Recognitions for Scientific Engagement, GSK Pharmaceutical Ltd., India (2021)
  2. Winner, Maiden IJME Young Bioethicist and Changemaker Award, IJME and FMES, Mumbai (2019)
  3. ISRPTJIPMER Medal for Best Poster Presentation, 11th ISRPTCON, Kolkata (2019)
  4. ISRPT Medal for Best Oral Presentation, 11th ISRPTCON, Kolkata (2019)
  5. Award for Best Critical Appraisal and Quiz (Runners-up), 2nd EBCCON, Chennai (2019)
  6. Second Prize, Research Presentation, 4th Research Day, JIPMER, Puducherry (2019)
  7. Rabindra Mandanha Prize for Best PG Research Paper (Basic Science), CMC Vellore (2016)
  8. Second Prize, Three Minute Thesis Competition, CMC Vellore (2016)
  9. Dr. Asim Kumar Biswas Memorial Scholarship Award, NRS Medical College and Hospital, Kolkata (2011)
  10. Runners-up, 22nd Indian Academy of Pediatrics Quiz for Undergraduates (2009)
  11. National Certificate of Merit, School-leaving Examination, Government of West Bengal (2006)

International Awards

  1. Long-Term Fellowship Abroad, Department of Health Research, MoHFW, Govt. of India (2025)
  2. Travel Grant 19th Congress of the International Headache Society (IHS), Dublin, Ireland (2019) (1,000)
  3. Travel Grant 15th International Congress of IATDMCT, Kyoto, Japan (2017) (USD 2,000)
  4. Travel Grant 33rd ICPE, Montreal, Canada (2017) (USD 2,200)
  5. Travel Grant 10th ACPE, Brisbane, Australia (2017) (AUD 1,720)
  6. Travel Grant 24th ISCOMS, Groningen, Netherlands (2017) (550)
  7. Travel Grant 7th ISPOR Asia-Pacific Conference, Singapore (2016) (USD 2,500)

 

Projects

As Principal investigator

  1. Technical Resource Centre (Centre for Evidence for Guidelines) [Funding Agency: Department of Health Research (DHR)(20242029)]
  2. Clinical Utility and Cost-Effectiveness of Pharmacogenomics-Assisted Treatment in Treatment-Resistant Schizophrenia [Funding Agency: ICMR(20242027)
  3. Pharmacogenomics-Assisted Schizophrenia Management: A Hybrid Type 2 Effectiveness-Implementation Study [Funding Agency: ICMR(20232026)]
  4. Efficacy of Adjunct Probiotics in Elderly Patients with Moderate Unipolar Depression: A Randomized Controlled Trial [Funding Agency: DHR(20232025)]
  5. Burden, Risk Factors, and Service Needs of People with Non-Fatal Opioid Poisoning [Funding Agency: ICMR(20232025)]
  6. Facilitators and Barriers for Uptake of COVID-19 Vaccine Precaution Dose
    [Funding Agency: ICMR (20222023)]
     

As Co-investigator

  1. Phase IIa RCT on Oxfendazole as a Macro-filaricidal Drug [Funding Agency: Drugs for Neglected Diseases initiative (DNDi) (20242026)]
  2. Evaluation of Influenza and Pneumococcal Vaccination in the Elderly An RCT [Funding Agency: ICMR(20242026)]
  3. Mental Health Issues among Mine Workers of Eastern Coalfields Ltd., West Bengal [Funding Agency: ICMR(20232025)]
  4. Development and Application of Frailty Management Model for Elderly
    [Funding Agency: ICMR (20242026)]
  5. Role of Stem Cells in ARDS A Systematic Review and Meta-analysis
    [Funding Agency: DHR(2023)]
  6. Evaluation of the Efficacy of Pilex Forte in Common Anorectal Conditions (Clinical Research Coordinator CRC) [Funding Agency: The Himalaya Drug Company(20182019)]
  7. Lithium Prophylaxis in Early-Onset Bipolar Disorder: A Descriptive Study
    [Funding Agency: SERB(20172020)]
  8. Association of Vitamin D Level with Vascular Functions in T2DM Patients with CKD [Funding Agency: Endocrine Society of TN & Puducherry(20192020)]
     

Students

Nil

Travel to foreign countries

  1. Long-Term Fellowship Abroad, Department of Health Research, MoHFW, Govt. of India (2025)
  2. 19th Congress of the IHS, Dublin, Ireland (2019)
  3. 15th International Congress of IATDMCT, Kyoto, Japan (2017)
  4. Travel Grant 33rd ICPE, Montreal, Canada (2017)
  5. Travel Grant 7th ISPOR Asia-Pacific Conference, Singapore (2016)
     

Publications

2025

  1. Majhi, A, Pakrashy, S., Paul, S., Misra, S., Sutradhar, D., Maurya, P. K., (2025). Design and synthesis of novel triazole based small molecules mimicking HDAC as new modular drugs candidate against Omicron and Future variants of SAES-COV-2.Indian Journal of Chemistry (Article in Press).

2024

  1. Basu, A., Dutta, A. K., Bagepally, B. S., Das, S., Cherian, J. J., Roy, S., Maurya, P. K., Saha, I., Sukumaran, D., Rina, K., Mandal, S., Sarkar, S., Kalita, M., Bhowmik, K., Saha, A., & Chakrabarti, A. (2024). Pharmacogenomics-assisted schizophrenia management: A hybrid type 2 effectiveness implementation study protocol to compare the clinical utility, cost-effectiveness, and barriers. PLoS ONE, 19(4 April), e0300511-e0300511.  https://doi.org/10.1371/journal.pone.0300511
  2. Misra, S., Pakrashy, S., Paul, S., Maurya, P. K., Sardar, P. S., Bose, A., & Majhi, A. (2024). Interaction of a new triazole compound with Serum albumins and Proteolytic enzyme Bromelain by Steady state fluorescence and Molecular docking techniques. Indian Journal of Biochemistry and Biophysics, 61(5), 305-313. https://doi.org/10.56042/ijbb.v61i5.6123
  3. Pakrashy, S., Chakraborty, S., Manna, S., Nanda Goswami, J., Bhattacharya, B., Emmerling, F., Mandal, J., Misra, S., Maiti Choudhury, S., Okla, M. K., Bose, A., Maurya, P. K., Majhi, A., & Dolai, M. (2024). Inhibition of Human Colorectal Cancer by a Natural Product 7-Acetylhorminone and Interactions with BSA/HSA: Multispectral Analysis and In Silico and In Vitro Studies. ACS Applied Bio Materials, 7(5), 3414-3430. https://doi.org/10.1021/acsabm.4c00335
  4. Pakrashy, S., Majhi, A., & Maurya, P. K. (2024). Embelin as an alternative reference standard for Delta-9-Tetrahydrocannibinol. Indian Journal of Chemistry, 63(4), 390-393. https://doi.org/10.56042/ijc.v63i4.7084

2023

  1. Maurya, P. K., Chakrabarti A, & Saha A. (2023). Chromium toxicity among leather industry workers in Kolkata-a Pilot Study. Int. J. Occup. Safety Health, 13(2), 140-145. https://doi.org/10.3126/ijosh
  2. Maurya, P. K., Yadav, A., & Maurya, P.K. (2023). HPLC analysis of biomarkers of Toluene and Xylene in human urine samples. International Journal of Occupational Safety and Health, 13(3), 331-337. https://doi.org/10.3126/ijosh.v13i3.46615
  3. Misra, S., Paul, S., Pakrashy, S., Ghosh, S., Naskar, S., Maurya, P. K., Sardar, P. S., Venkateswarlu, K., Bose, A., & Majhi, A. (2023). DE-NOVO DRUG DESIGN OF NOVEL 1,2,3-TRIAZOLE-NAPHTHAMIDE AS AN INHIBITOR OF SARS-COV-2 MAIN PROTEASE: SYNTHESIS, BIOINFORMATICS AND BIOPHYSICAL STUDIES. Indian Journal of Chemistry, 62(10), 1001-1011. https://doi.org/10.56042/ijc.v62i10.1578

2020

  1. Zhang, Y., Vaidya, N., Iyengar, U., Sharma, E., Holla, B., Ahuja, C. K., Barker, G. J., Basu, D., Bharath, R. D., Chakrabarti, A., Desrivieres, S., Elliott, P., Fernandes, G., Gourisankar, A., Heron, J., Hickman, M., Jacob, P., Jain, S., Jayarajan, D., ... Bhavana, B. R. (2020). The Consortium on Vulnerability to Externalizing Disorders and Addictions (c-VEDA): an accelerated longitudinal cohort of children and adolescents in India. Molecular Psychiatry, 25(8), 1618-1630. https://doi.org/10.1038/s41380-020-0656-1

2012

  1. Nageswara Rao, R., Maurya, P. K., & Guruprasad, K. (2012). Evaluation of polysaccharide-based chiral stationary phases in quality control of (S)-mirtazapine. Biomedical Chromatography, 26(2), 142-146.  https://doi.org/10.1002/bmc.1638

2011

  1. Nageswara Rao, R., Guru Prasad, K., Gangu Naidu, C., & Maurya, P. K. (2011). Development of a validated liquid chromatographic method for determination of related substances of telmisartan in bulk drugs and formulations. Journal of Pharmaceutical and Biomedical Analysis, 56(3), 471-478.  https://doi.org/10.1016/j.jpba.2011.05.043
  2. Nageswara Rao, R., Vali, R. M., Ramachandra, B., & Maurya, P. K. (2011). Rapid determination of rifaximin on dried blood spots by LC-ESI-MS. Biomedical Chromatography, 25(11), 1201-1207. https://doi.org/10.1002/bmc.1591
  3. Rao, R. N., Bompelli, S., & Maurya, P. K. (2011). High-performance liquid chromatographic determination of anti- hypertensive drugs on dried blood spots using a fluorescence detector - method development and validation. Biomedical Chromatography, 25(11), 1252-1259. https://doi.org/10.1002/bmc.1599
  4. Rao, R. N., Maurya, P. K., & Khalid, S. (2011). Development of a molecularly imprinted polymer for selective extraction followed by liquid chromatographic determination of sitagliptin in rat plasma and urine. Talanta, 85(2), 950-957. https://doi.org/10.1016/j.talanta.2011.05.002
  5. Rao, R. N., Maurya, P. K., Kuntamukkala, R., Vitthal, W. D., & Talluri, M. V. N. K. (2011). Molecularly imprinted polymer for selective extraction of 3-methylflavone-8-carboxylic acid from human urine followed by its determination using zwitterionic hydrophilic interaction liquid chromatography. Journal of Separation Science, 34(22), 3265-3271.  https://doi.org/10.1002/jssc.201100560
  6. Rao, R. N., Maurya, P. K., Shinde, D. D., & Agwane, S. B. (2011). Reversed-phase liquid chromatographic determination of tramiprosate in rat plasma using evaporative light scattering detector. Biomedical Chromatography, 25(8), 925-929.  https://doi.org/10.1002/bmc.1546
  7. Rao, R. N., Maurya, P. K., Shinde, D. D., & Khalid, S. (2011). Precolumn derivatization followed by liquid chromatographic separation and determination of tramiprosate in rat plasma by fluorescence detector: Application to pharmacokinetics. Journal of Pharmaceutical and Biomedical Analysis, 55(2), 282-287.  https://doi.org/10.1016/j.jpba.2011.01.013

2010

  1. Rao, R. N., Maurya, P. K., Ramesh, M., Srinivas, R., & Agwane, S. B. (2010). Development of a validated high-throughput LC-ESI-MS method for determination of sirolimus on dried blood spots. Biomedical Chromatography, 24(12), 1356-1364. https://doi.org/10.1002/bmc.1450
  2. Rao, R. N., Maurya, P. K., & Shinde, D. D. (2010). Development of a validated LC method for enantiomeric separation and determination of adrafinil and its related substances on a Chiralcel OJ-H column connected to PDA and polarimetric detectors in series. Biomedical Chromatography, 24(11), 1228-1233.  https://doi.org/10.1002/bmc.1432

2009

  1. Nageswara Rao, R., Maurya, P. K., & Narasa Raju, A. (2009). Isolation and characterization of a potential process related impurity of phenazopyridine HCl by preparative HPLC followed by MS-MS and 2D-NMR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis, 49(5), 1287-1291.  https://doi.org/10.1016/j.jpba.2009.03.004
  2. Rao, R. N., Talluri, M. V. N. K., & Maurya, P. K. (2009). Separation of stereoisomers of sertraline and its related enantiomeric impurities on a dimethylated β-cyclodextrin stationary phase by HPLC. Journal of Pharmaceutical and Biomedical Analysis, 50(3), 281-286. https://doi.org/10.1016/j.jpba.2009.04.038